Role of Claudin-5 in the Attenuation of Murine Acute Lung Injury by Simvastatin

The statins are now recognized to have pleiotropic properties, including augmentation of endothelial barrier function. To explore the mechanisms involved, we investigated the effect of simvastatin on endothelial cell (EC) tight junctions. Western blotting of human pulmonary artery ECs treated with s...

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Autori principali: Chen, Weiguo, Sharma, Rajesh, Rizzo, Alicia N., Siegler, Jessica H., Garcia, Joe G. N., Jacobson, Jeffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930946/
https://ncbi.nlm.nih.gov/pubmed/24028293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0058OC
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