Role of Claudin-5 in the Attenuation of Murine Acute Lung Injury by Simvastatin

The statins are now recognized to have pleiotropic properties, including augmentation of endothelial barrier function. To explore the mechanisms involved, we investigated the effect of simvastatin on endothelial cell (EC) tight junctions. Western blotting of human pulmonary artery ECs treated with s...

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Dades bibliogràfiques
Autors principals: Chen, Weiguo, Sharma, Rajesh, Rizzo, Alicia N., Siegler, Jessica H., Garcia, Joe G. N., Jacobson, Jeffrey R.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930946/
https://ncbi.nlm.nih.gov/pubmed/24028293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0058OC
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