Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), an illness characterized by life-threatening vascular leak, is a significant cause of morbidity and mortality in critically ill patients. Recent preclinical studies and clinical observations have suggested a potential role for the che...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Rizzo, Alicia N., Sammani, Saad, Esquinca, Adilene E., Jacobson, Jeffrey R., Garcia, Joe G. N., Letsiou, Eleftheria, Dudek, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669340/
https://ncbi.nlm.nih.gov/pubmed/26432864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00031.2015
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