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Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress
Simvastatin, an HMG-CoA reductase inhibitor, has lung vascular-protective effects that are associated with decreased agonist-induced integrin β4 (ITGB4) tyrosine phosphorylation. Accordingly, we hypothesized that endothelial cell (EC) protection by simvastatin is dependent on these effects and sough...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647208/ https://ncbi.nlm.nih.gov/pubmed/26572585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16529 |
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