UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo

Increasing evidence suggests an important role for deubiquitinating enzymes (DUBs) in modulating a variety of biological functions and diseases. We previously identified the upregulation of the DUB ubiquitin carboxyl terminal hydrolase 1 (UCHL1) in murine ventilator-induced lung injury (VILI). Howev...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Mitra, Sumegha, Epshtein, Yulia, Sammani, Saad, Quijada, Hector, Chen, Weiguo, Bandela, Mounica, Desai, Ankit A., Garcia, Joe G.N., Jacobson, Jeffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238159/
https://ncbi.nlm.nih.gov/pubmed/33438509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00492.2020
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