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Enhanced Binding of Apolipoprotein A-I Variants Associated with Hypertriglyceridemia to Triglyceride-Rich Particles

Hypertriglyceridemia (HTG) is a common lipid abnormality in humans. However, its etiology remains largely unknown. It was shown that severe HTG can be induced in mice by overexpression of wild-type (WT) apolipoprotein E (apoE) or specific apoA-I mutants. Certain mutations in apoE4 were found to affe...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Gorshkova, Irina N., Atkinson, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128146/
https://ncbi.nlm.nih.gov/pubmed/21288012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200158b
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