Загрузка...
Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720
[Image: see text] The first enantioselective synthesis of chiral isosteric phosphonate analogues of FTY720 is described. One of these analogues, FTY720-(E)-vinylphosphonate (S)-5, but not its R enantiomer, elicited a potent anti-apoptotic effect in intestinal epithelial cells, suggesting that it exe...
Сохранить в:
| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747615/ https://ncbi.nlm.nih.gov/pubmed/19296586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo900023u |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|