Modeling clinical and molecular covariates of mutational process activity in cancer

بواسطة Robinson, Welles, Sharan, Roded, Leiserson, Mark D M
الحاوية / القاعدة Bioinformatics (2019)

A weighted exact test for mutually exclusive mutations in cancer

بواسطة Leiserson, Mark D.M., Reyna, Matthew A., Raphael, Benjamin J.
الحاوية / القاعدة Bioinformatics (2016)

Hierarchical HotNet: identifying hierarchies of altered subnetworks

بواسطة Reyna, Matthew A, Leiserson, Mark D M, Raphael, Benjamin J
الحاوية / القاعدة Bioinformatics (2018)

Simultaneous Identification of Multiple Driver Pathways in Cancer

بواسطة Leiserson, Mark D. M., Blokh, Dima, Sharan, Roded, Raphael, Benjamin J.
منشور في 2013

Precision Oncology: The Road Ahead

بواسطة Senft, Daniela, Leiserson, Mark D M, Ruppin, Eytan, Ronai, Zéev A
الحاوية / القاعدة Trends Mol Med (2017)

DNA REPAIR FOOTPRINT UNCOVERS CONTRIBUTION OF DNA REPAIR MECHANISM TO MUTATIONAL SIGNATURES

بواسطة Wojtowicz, Damian, Leiserson, Mark D.M., Sharan, Roded, Przytycka, Teresa M.
الحاوية / القاعدة Pac Symp Biocomput (2020)

Inferring Mechanisms of Compensation from E-MAP and SGA Data Using Local Search Algorithms for Max Cut

بواسطة Leiserson, Mark D.M., Tatar, Diana, Cowen, Lenore J., Hescott, Benjamin J.
منشور في 2011

Erratum to: CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer

بواسطة Leiserson, Mark D. M., Wu, Hsin-Ta, Vandin, Fabio, Raphael, Benjamin J.
الحاوية / القاعدة Genome Biol (2016)

Criticality in tumor evolution and clinical outcome

بواسطة Persi, Erez, Wolf, Yuri I., Leiserson, Mark D. M., Koonin, Eugene V., Ruppin, Eytan
الحاوية / القاعدة Proc Natl Acad Sci U S A (2018)

A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer

بواسطة Sason, Itay, Wojtowicz, Damian, Robinson, Welles, Leiserson, Mark D.M., Przytycka, Teresa M., Sharan, Roded
الحاوية / القاعدة iScience (2020)

Functional protein representations from biological networks enable diverse cross-species inference

بواسطة Fan, Jason, Cannistra, Anthony, Fried, Inbar, Lim, Tim, Schaffner, Thomas, Crovella, Mark, Hescott, Benjamin, Leiserson, Mark D M
الحاوية / القاعدة Nucleic Acids Res (2019)

Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer

بواسطة Wojtowicz, Damian, Sason, Itay, Huang, Xiaoqing, Kim, Yoo-Ah, Leiserson, Mark D. M., Przytycka, Teresa M., Sharan, Roded
الحاوية / القاعدة Genome Med (2019)

Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

بواسطة Kim, Yoo-Ah, Wojtowicz, Damian, Sarto Basso, Rebecca, Sason, Itay, Robinson, Welles, Hochbaum, Dorit S., Leiserson, Mark D. M., Sharan, Roded, Vadin, Fabio, Przytycka, Teresa M.
الحاوية / القاعدة Genome Med (2020)

A multifactorial model of T cell expansion and durable clinical benefit in response to a PD-L1 inhibitor

بواسطة Leiserson, Mark D. M., Syrgkanis, Vasilis, Gilson, Amy, Dudik, Miroslav, Gillett, Sharon, Chayes, Jennifer, Borgs, Christian, Bajorin, Dean F., Rosenberg, Jonathan E., Funt, Samuel, Snyder, Alexandra, Mackey, Lester
الحاوية / القاعدة PLoS One (2018)

Pan-Cancer Network Analysis Identifies Combinations of Rare Somatic Mutations across Pathways and Protein Complexes

بواسطة Leiserson, Mark D.M., Vandin, Fabio, Wu, Hsin-Ta, Dobson, Jason R., Eldridge, Jonathan V., Thomas, Jacob L., Papoutsaki, Alexandra, Kim, Younhun, Niu, Beifang, McLellan, Michael, Lawrence, Michael S., Gonzalez-Perez, Abel, Tamborero, David, Cheng, Yuwei, Ryslik, Gregory A., Lopez-Bigas, Nuria, Getz, Gad, Ding, Li, Raphael, Benjamin J.
الحاوية / القاعدة Nat Genet (2014)

Mutational landscape and significance across 12 major cancer types

بواسطة Kandoth, Cyriac, McLellan, Michael D., Vandin, Fabio, Ye, Kai, Niu, Beifang, Lu, Charles, Xie, Mingchao, Zhang, Qunyuan, McMichael, Joshua F., Wyczalkowski, Matthew A., Leiserson, Mark D. M., Miller, Christopher A., Welch, John S., Walter, Matthew J., Wendl, Michael C., Ley, Timothy J., Wilson, Richard K., Raphael, Benjamin J., Ding, Li
منشور في 2013

Integrated Analysis of Germline and Somatic Variants in Ovarian Cancer

بواسطة Kanchi, Krishna L., Johnson, Kimberly J., Lu, Charles, McLellan, Michael D., Leiserson, Mark D.M., Wendl, Michael C., Zhang, Qunyuan, Koboldt, Daniel C., Xie, Mingchao, Kandoth, Cyriac, McMichael, Joshua F., Wyczalkowski, Matthew A., Larson, David E., Schmidt, Heather K., Miller, Christopher A., Fulton, Robert S., Spellman, Paul T., Mardis, Elaine R., Druley, Todd E., Graubert, Timothy A., Goodfellow, Paul J., Raphael, Benjamin J., Wilson, Richard K., Ding, Li
منشور في 2014

Patterns and functional implications of rare germline variants across 12 cancer types

بواسطة Lu, Charles, Xie, Mingchao, Wendl, Michael C., Wang, Jiayin, McLellan, Michael D., Leiserson, Mark D. M., Huang, Kuan-lin, Wyczalkowski, Matthew A., Jayasinghe, Reyka, Banerjee, Tapahsama, Ning, Jie, Tripathi, Piyush, Zhang, Qunyuan, Niu, Beifang, Ye, Kai, Schmidt, Heather K., Fulton, Robert S., McMichael, Joshua F., Batra, Prag, Kandoth, Cyriac, Bharadwaj, Maheetha, Koboldt, Daniel C., Miller, Christopher A., Kanchi, Krishna L., Eldred, James M., Larson, David E., Welch, John S., You, Ming, Ozenberger, Bradley A., Govindan, Ramaswamy, Walter, Matthew J., Ellis, Matthew J., Mardis, Elaine R., Graubert, Timothy A., Dipersio, John F., Ley, Timothy J., Wilson, Richard K., Goodfellow, Paul J., Raphael, Benjamin J., Chen, Feng, Johnson, Kimberly J., Parvin, Jeffrey D., Ding, Li
الحاوية / القاعدة Nat Commun (2015)

Comprehensive Molecular Characterization of Papillary Renal Cell Carcinoma

بواسطة Linehan, W. Marston, Spellman, Paul T., Ricketts, Christopher J., Creighton, Chad J., Fei, Suzanne S., Davis, Caleb, Wheeler, David A., Murray, Bradley A., Schmidt, Laura, Vocke, Cathy D., Peto, Myron, Al Mamun, Abu Amar M., Shinbrot, Eve, Sethi, Anurag, Brooks, Samira, Rathmell, W. Kimryn, Brooks, Angela N., Hoadley, Katherine A., Robertson, A. Gordon, Brooks, Denise, Bowlby, Reanne, Sadeghi, Sara, Shen, Hui, Weisenberger, Daniel J., Bootwalla, Moiz, Baylin, Stephen B., Laird, Peter W., Cherniack, Andrew D., Saksena, Gordon, Haake, Scott, Li, Jun, Liang, Han, Lu, Yiling, Mills, Gordon B., Akbani, Rehan, Leiserson, Mark D.M., Raphael, Benjamin J., Anur, Pavana, Bottaro, Donald, Albiges, Laurence, Barnabas, Nandita, Choueiri, Toni K., Czerniak, Bogdan, Godwin, Andrew K., Hakimi, A. Ari, Ho, Thai, Hsieh, James, Ittmann, Michael, Kim, William Y., Krishnan, Bhavani, Merino, Maria J., Mills Shaw, Kenna R., Reuter, Victor E., Reznik, Ed, Shelley, Carl Simon, Shuch, Brian, Signoretti, Sabina, Srinivasan, Ramaprasad, Tamboli, Pheroze, Thomas, George, Tickoo, Satish, Burnett, Kenneth, Crain, Daniel, Gardner, Johanna, Lau, Kevin, Mallery, David, Morris, Scott, Paulauskis, Joseph D., Penny, Robert J., Shelton, Candace, Shelton, W. Troy, Sherman, Mark, Thompson, Eric, Yena, Peggy, Avedon, Melissa T., Bowen, Jay, Gastier-Foster, Julie M., Gerken, Mark, Leraas, Kristen M., Lichtenberg, Tara M., Ramirez, Nilsa C., Santos, Tracie, Wise, Lisa, Zmuda, Erik, Demchok, John A., Felau, Ina, Hutter, Carolyn M., Sheth, Margi, Sofia, Heidi J., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Zhang, Jiashan (Julia), Ayala, Brenda, Baboud, Julien, Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Naresh, Rashi, Pihl, Todd, Sun, Qiang, Wan, Yunhu, Wu, Ye, Ally, Adrian, Balasundaram, Miruna, Balu, Saianand, Beroukhim, Rameen, Bodenheimer, Tom, Buhay, Christian, Butterfield, Yaron S.N., Carlsen, Rebecca, Carter, Scott L., Chao, Hsu, Chuah, Eric, Clarke, Amanda, Covington, Kyle R., Dahdouli, Mahmoud, Dewal, Ninad, Dhalla, Noreen, Doddapaneni, HarshaVardhan, Drummond, Jennifer, Gabriel, Stacey B., Gibbs, Richard A., Guin, Ranabir, Hale, Walker, Hawes, Alicia, Hayes, D. Neil, Holt, Robert A., Hoyle, Alan P., Jefferys, Stuart R., Jones, Steven J.M., Jones, Corbin D., Kalra, Divya, Kovar, Christie, Lewis, Lora, Li, Jie, Ma, Yussanne, Marra, Marco A., Mayo, Michael, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Moore, Richard A., Morton, Donna, Mose, Lisle E., Mungall, Andrew J., Muzny, Donna, Parker, Joel S., Perou, Charles M., Roach, Jeffrey, Schein, Jacqueline E., Schumacher, Steven E., Shi, Yan, Simons, Janae V., Sipahimalani, Payal, Skelly, Tara, Soloway, Matthew G., Sougnez, Carrie, Tam, Angela, Tan, Donghui, Thiessen, Nina, Veluvolu, Umadevi, Wang, Min, Wilkerson, Matthew D., Wong, Tina, Wu, Junyuan, Xi, Liu, Zhou, Jane, Bedford, Jason, Chen, Fengju, Fu, Yao, Gerstein, Mark, Haussler, David, Kasaian, Katayoon, Lai, Phillip, Ling, Shiyun, Radenbaugh, Amie, Van Den Berg, David, Weinstein, John N., Zhu, Jingchun, Albert, Monique, Alexopoulou, Iakovina, Andersen, Jeremiah J, Auman, J. Todd, Bartlett, John, Bastacky, Sheldon, Bergsten, Julie, Blute, Michael L., Boice, Lori, Bollag, Roni J., Boyd, Jeff, Castle, Erik, Chen, Ying-Bei, Cheville, John C., Curley, Erin, Davies, Benjamin, DeVolk, April, Dhir, Rajiv, Dike, Laura, Eckman, John, Engel, Jay, Harr, Jodi, Hrebinko, Ronald, Huang, Mei, Huelsenbeck-Dill, Lori, Iacocca, Mary, Jacobs, Bruce, Lobis, Michael, Maranchie, Jodi K., McMeekin, Scott, Myers, Jerome, Nelson, Joel, Parfitt, Jeremy, Parwani, Anil, Petrelli, Nicholas, Rabeno, Brenda, Roy, Somak, Salner, Andrew L., Slaton, Joel, Stanton, Melissa, Thompson, R. Houston, Thorne, Leigh, Tucker, Kelinda, Weinberger, Paul M., Winemiller, Cythnia, Zach, Leigh Anne, Zuna, Rosemary
الحاوية / القاعدة N Engl J Med (2015)