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Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer
Knowing the activity of the mutational processes shaping a cancer genome may provide insight into tumorigenesis and personalized therapy. It is thus important to characterize the signatures of active mutational processes in patients from their patterns of single base substitutions. However, mutation...
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| Publicado no: | Genome Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660659/ https://ncbi.nlm.nih.gov/pubmed/31349863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0659-1 |
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