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Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer
Knowing the activity of the mutational processes shaping a cancer genome may provide insight into tumorigenesis and personalized therapy. It is thus important to characterize the signatures of active mutational processes in patients from their patterns of single base substitutions. However, mutation...
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| Pubblicato in: | Genome Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660659/ https://ncbi.nlm.nih.gov/pubmed/31349863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0659-1 |
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