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BeWith: A Between-Within method to discover relationships between cancer modules via integrated analysis of mutual exclusivity, co-occurrence and functional interactions

The analysis of the mutational landscape of cancer, including mutual exclusivity and co-occurrence of mutations, has been instrumental in studying the disease. We hypothesized that exploring the interplay between co-occurrence, mutual exclusivity, and functional interactions between genes will furth...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Dao, Phuong, Kim, Yoo-Ah, Wojtowicz, Damian, Madan, Sanna, Sharan, Roded, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638227/
https://ncbi.nlm.nih.gov/pubmed/29023534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005695
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