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A weighted exact test for mutually exclusive mutations in cancer
Motivation: The somatic mutations in the pathways that drive cancer development tend to be mutually exclusive across tumors, providing a signal for distinguishing driver mutations from a larger number of random passenger mutations. This mutual exclusivity signal can be confounded by high and highly...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013919/ https://ncbi.nlm.nih.gov/pubmed/27587696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw462 |
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