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Modeling Mutual Exclusivity of Cancer Mutations

In large collections of tumor samples, it has been observed that sets of genes that are commonly involved in the same cancer pathways tend not to occur mutated together in the same patient. Such gene sets form mutually exclusive patterns of gene alterations in cancer genomic data. Computational appr...

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Bibliografische gegevens
Hoofdauteurs: Szczurek, Ewa, Beerenwinkel, Niko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967923/
https://ncbi.nlm.nih.gov/pubmed/24675718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003503
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