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Modeling Mutual Exclusivity of Cancer Mutations

In large collections of tumor samples, it has been observed that sets of genes that are commonly involved in the same cancer pathways tend not to occur mutated together in the same patient. Such gene sets form mutually exclusive patterns of gene alterations in cancer genomic data. Computational appr...

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Detalhes bibliográficos
Main Authors: Szczurek, Ewa, Beerenwinkel, Niko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967923/
https://ncbi.nlm.nih.gov/pubmed/24675718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003503
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