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Simultaneous Identification of Multiple Driver Pathways in Cancer
Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662702/ https://ncbi.nlm.nih.gov/pubmed/23717195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003054 |
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