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Finding driver pathways in cancer: models and algorithms
BACKGROUND: Cancer sequencing projects are now measuring somatic mutations in large numbers of cancer genomes. A key challenge in interpreting these data is to distinguish driver mutations, mutations important for cancer development, from passenger mutations that have accumulated in somatic cells bu...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544164/ https://ncbi.nlm.nih.gov/pubmed/22954134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-7-23 |
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