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Finding driver pathways in cancer: models and algorithms

BACKGROUND: Cancer sequencing projects are now measuring somatic mutations in large numbers of cancer genomes. A key challenge in interpreting these data is to distinguish driver mutations, mutations important for cancer development, from passenger mutations that have accumulated in somatic cells bu...

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Autors principals: Vandin, Fabio, Upfal, Eli, Raphael, Benjamin J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544164/
https://ncbi.nlm.nih.gov/pubmed/22954134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-7-23
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