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Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine
High-throughput DNA sequencing is revolutionizing the study of cancer and enabling the measurement of the somatic mutations that drive cancer development. However, the resulting sequencing datasets are large and complex, obscuring the clinically important mutations in a background of errors, noise,...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978567/ https://ncbi.nlm.nih.gov/pubmed/24479672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm524 |
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