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Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine

High-throughput DNA sequencing is revolutionizing the study of cancer and enabling the measurement of the somatic mutations that drive cancer development. However, the resulting sequencing datasets are large and complex, obscuring the clinically important mutations in a background of errors, noise,...

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Sonraí Bibleagrafaíochta
Main Authors: Raphael, Benjamin J, Dobson, Jason R, Oesper, Layla, Vandin, Fabio
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978567/
https://ncbi.nlm.nih.gov/pubmed/24479672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm524
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