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Identifying simultaneous rearrangements in cancer genomes

MOTIVATION: The traditional view of cancer evolution states that a cancer genome accumulates a sequential ordering of mutations over a long period of time. However, in recent years it has been suggested that a cancer genome may instead undergo a one-time catastrophic event, such as chromothripsis, w...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Oesper, Layla, Dantas, Simone, Raphael, Benjamin J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860217/
https://ncbi.nlm.nih.gov/pubmed/29186385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx745
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