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Reconstructing cancer genomes from paired-end sequencing data

BACKGROUND: A cancer genome is derived from the germline genome through a series of somatic mutations. Somatic structural variants - including duplications, deletions, inversions, translocations, and other rearrangements - result in a cancer genome that is a scrambling of intervals, or "blocks&...

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Detalles Bibliográficos
Autores principales: Oesper, Layla, Ritz, Anna, Aerni, Sarah J, Drebin, Ryan, Raphael, Benjamin J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358655/
https://ncbi.nlm.nih.gov/pubmed/22537039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S6-S10
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