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Reconstruction of clonal trees and tumor composition from multi-sample sequencing data
Motivation: DNA sequencing of multiple samples from the same tumor provides data to analyze the process of clonal evolution in the population of cells that give rise to a tumor. Results: We formalize the problem of reconstructing the clonal evolution of a tumor using single-nucleotide mutations as t...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542783/ https://ncbi.nlm.nih.gov/pubmed/26072510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv261 |
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