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Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers

At the root of the so-called precision medicine or precision oncology, which is our focus here, is the hypothesis that cancer treatment would be considerably better if therapies were guided by a tumor’s genomic alterations. This hypothesis has sparked major initiatives focusing on whole-genome and/o...

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Publicat a:PLoS Comput Biol
Autors principals: Nussinov, Ruth, Jang, Hyunbum, Tsai, Chung-Jung, Cheng, Feixiong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438456/
https://ncbi.nlm.nih.gov/pubmed/30921324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006658
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