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Simultaneous Identification of Multiple Driver Pathways in Cancer

Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...

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Bibliografische gegevens
Hoofdauteurs: Leiserson, Mark D. M., Blokh, Dima, Sharan, Roded, Raphael, Benjamin J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662702/
https://ncbi.nlm.nih.gov/pubmed/23717195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003054
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