Nuclear respiratory factor 2 induces SIRT3 expression

por Satterstrom, F Kyle, Swindell, William R, Laurent, Gaëlle, Vyas, Sejal, Bulyk, Martha L, Haigis, Marcia C
Publicado no Aging Cell (2015)

HDAC6 and SIRT2 regulate the acetylation state and oncogenic activity of mutant K-RAS

por Yang, Moon Hee, Laurent, Gaelle, Bause, Alexandra S., Spang, Robert, German, Natalie, Haigis, Marcia C., Haigis, Kevin M.
Publicado em 2013

AP-1 Transcription Factor JunD Confers Protection from Accelerated Nephrotoxic Nephritis and Control Podocyte-Specific Vegfa Expression

por Cook, H. Terence, Tarzi, Ruth, D'Souza, Zelpha, Laurent, Gaelle, Lin, Wei-Chou, Aitman, Timothy J., Mechta-Grigoriou, Fatima, Behmoaras, Jacques
Publicado em 2011

SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

por Laurent, Gaëlle, de Boer, Vincent C. J., Finley, Lydia W. S., Sweeney, Meredith, Lu, Hong, Schug, Thaddeus T., Cen, Yana, Jeong, Seung Min, Li, Xiaoling, Sauve, Anthony A., Haigis, Marcia C.
Publicado em 2013

Regulation of RAS oncogenicity by acetylation

por Yang, Moon Hee, Nickerson, Seth, Kim, Eric T., Liot, Caroline, Laurent, Gaelle, Spang, Robert, Philips, Mark R., Shan, Yibing, Shaw, David E., Bar-Sagi, Dafna, Haigis, Marcia C., Haigis, Kevin M.
Publicado em 2012

SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase

por Laurent, Gaëlle, German, Natalie J, Saha, Asish K, de Boer, Vincent CJ, Fischer, Frank, Boanca, Gina, Dephoure, Noah, Vaitheesvaran, Bhavapriya, Davies, Michael, Gygi, Steven P, Muoio, Deborah M, Kurland, Irwin J, Steegborn, Clemens, Ruderman, Neil B, Haigis, Marcia C
Publicado em 2012

SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

por Zaganjor, Elma, Yoon, Haejin, Spinelli, Jessica B., Nunn, Elizabeth R., Laurent, Gaëlle, Keskinidis, Paulina, Sivaloganathan, Suganja, Joshi, Shakchhi, Notarangelo, Giulia, Mulei, Stacy, Chvasta, Mathew T., Tucker, Sarah A., Kalafut, Krystle, van de Ven, Robert A.H., Clish, Clary B., Haigis, Marcia C.
Publicado no Cell Rep (2021)

Systemic elevation of PTEN induces a tumor suppressive metabolic state

por Garcia-Cao, Isabel, Song, Min Sup, Hobbs, Robin M., Laurent, Gaelle, Giorgi, Carlotta, de Boer, Vincent C.J., Anastasiou, Dimitrios, Ito, Keisuke, Sasaki, Atsuo T., Rameh, Lucia, Carracedo, Arkaitz, Vander Heiden, Matthew G., Cantley, Lewis C., Pinton, Paolo, Haigis, Marcia C., Pandolfi, Pier Paolo
Publicado em 2012

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

por Egerman, Marc A., Cadena, Samuel M., Gilbert, Jason A., Meyer, Angelika, Nelson, Hallie N., Swalley, Susanne E., Mallozzi, Carolyn, Jacobi, Carsten, Jennings, Lori L., Clay, Ieuan, Laurent, Gaëlle, Ma, Shenglin, Brachat, Sophie, Lach-Trifilieff, Estelle, Shavlakadze, Tea, Trendelenburg, Anne-Ulrike, Brack, Andrew S., Glass, David J.
Publicado no Cell Metab (2015)

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

por German, Natalie J., Yoon, Haejin, Yusuf, Rushdia Z., Murphy, J. Patrick, Finley, Lydia W.S., Laurent, Gaëlle, Haas, Wilhelm, Satterstrom, F. Kyle, Guarnerio, Jlenia, Zaganjor, Elma, Santos, Daniel, Pandolfi, Pier Paolo, Beck, Andrew H., Gygi, Steven P., Scadden, David T., Kaelin, William G., Haigis, Marcia C.
Publicado no Mol Cell (2016)

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase

por Laurent, Gaëlle, German, Natalie J., Saha, Asish K., de Boer, Vincent C. J., Davies, Michael, Koves, Timothy R., Dephoure, Noah, Fischer, Frank, Boanca, Gina, Vaitheesvaran, Bhavapriya, Lovitch, Scott B., Sharpe, Arlene H., Kurland, Irwin J., Steegborn, Clemens, Gygi, Steven P., Muoio, Deborah M., Ruderman, Neil B., Haigis, Marcia C.
Publicado em 2013

A metabolic prosurvival role for PML in breast cancer

por Carracedo, Arkaitz, Weiss, Dror, Leliaert, Amy K., Bhasin, Manoj, de Boer, Vincent C.J., Laurent, Gaelle, Adams, Andrew C., Sundvall, Maria, Song, Su Jung, Ito, Keisuke, Finley, Lydia S., Egia, Ainara, Libermann, Towia, Gerhart-Hines, Zachary, Puigserver, Pere, Haigis, Marcia C., Maratos-Flier, Elefteria, Richardson, Andrea L., Schafer, Zachary T., Pandolfi, Pier P.
Publicado em 2012

SIRT4 has tumor suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism

por Jeong, Seung Min, Xiao, Cuiying, Finley, Lydia W.S, Lahusen, Tyler, Souza, Amanda L., Pierce, Kerry, Li, Ying-Hua, Wang, Xiaoxu, Laurent, Gaëlle, German, Natalie J., Xu, Xiaoling, Li, Cuiling, Wang, Rui-Hong, Lee, Jaewon, Csibi, Alfredo, Cerione, Richard, Blenis, John, Clish, Clary B., Kimmelman, Alec, Deng, Chu-Xia, Haigis, Marcia C.
Publicado em 2013