Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle: Association With Changes in cAMP, Energy State, and Endogenous Fuel Mobilization

by Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ruderman, Neil B.
Published 2009

AMPK activation: a therapeutic target for type 2 diabetes?

by Coughlan, Kimberly A, Valentine, Rudy J, Ruderman, Neil B, Saha, Asish K
Published 2014

Insulin inhibits AMPK activity and phosphorylates AMPK Ser(485/491) through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

by Valentine, Rudy J., Coughlan, Kimberly A., Ruderman, Neil B., Saha, Asish K.
Published in Arch Biochem Biophys (2014)

Nutrient Excess in AMPK Downregulation and Insulin Resistance

by Coughlan, Kimberly A., Valentine, Rudy J., Ruderman, Neil B., Saha, Asish K.
Published in J Endocrinol Diabetes Obes (2013)

Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation?

by Saha, Asish K, Xu, X. Julia, Balon, Thomas W, Brandon, Amanda, Kraegen, Edward W, Ruderman, Neil B
Published 2011

AMPK and SIRT1: a long-standing partnership?

by Ruderman, Neil B., Julia Xu, X., Nelson, Lauren, Cacicedo, José M., Saha, Asish K., Lan, Fan, Ido, Yasuo
Published 2010

AMP-activated Protein Kinase Is Activated as a Consequence of Lipolysis in the Adipocyte: POTENTIAL MECHANISM AND PHYSIOLOGICAL RELEVANCE

by Gauthier, Marie-Soleil, Miyoshi, Hideaki, Souza, Sandra C., Cacicedo, José M., Saha, Asish K., Greenberg, Andrew S., Ruderman, Neil B.
Published 2008

Central Ghrelin Regulates Peripheral Lipid Metabolism in a Growth Hormone-Independent Fashion

by Sangiao-Alvarellos, Susana, Vázquez, María J., Varela, Luis, Nogueiras, Rubén, Saha, Asish K., Cordido, Fernando, López, Miguel, Diéguez, Carlos
Published 2009

Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender

by Lage, Ricardo, Vázquez, María J., Varela, Luis, Saha, Asish K., Vidal-Puig, Antonio, Nogueiras, Rubén, Diéguez, Carlos, López, Miguel
Published 2010

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle

by Saha, Asish K., Xu, X. Julia, Lawson, Ebony, Deoliveira, Rosangela, Brandon, Amanda E., Kraegen, Edward W., Ruderman, Neil B.
Published 2010

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells

by Coughlan, Kimberly A., Valentine, Rudy J., Sudit, Bella S., Allen, Katherine, Dagon, Yossi, Kahn, Barbara B., Ruderman, Neil B., Saha, Asish K.
Published in J Biol Chem (2016)

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

by Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Published 2002

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

by Suchankova, Gabriela, Nelson, Lauren E., Gerhart-Hines, Zachary, Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ido, Yasuo, Puigserver, Pere, Ruderman, Neil B.
Published 2008

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

by Harriman, Geraldine, Greenwood, Jeremy, Bhat, Sathesh, Huang, Xinyi, Wang, Ruiying, Paul, Debamita, Tong, Liang, Saha, Asish K., Westlin, William F., Kapeller, Rosana, Harwood, H. James
Published in Proc Natl Acad Sci U S A (2016)

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

by Ho, Linh, Titus, Allen Sam, Banerjee, Kushal Kr, George, Suji, Lin, Wei, Deota, Shaunak, Saha, Asish K., Nakamura, Ken, Gut, Philipp, Verdin, Eric, Kolthur-Seetharam, Ullas
Published 2013

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats

by Coughlan, Kimberly A., Balon, Thomas W., Valentine, Rudy J., Petrocelli, Robert, Schultz, Vera, Brandon, Amanda, Cooney, Gregory J., Kraegen, Edward W., Ruderman, Neil B., Saha, Asish K.
Published in PLoS One (2015)

Ablation of ARNT/HIF1β in Liver Alters Gluconeogenesis, Lipogenic Gene Expression, and Serum Ketones

by Wang, Xiaohui L., Suzuki, Ryo, Lee, Kevin, Tran, Thien, Gunton, Jenny E., Saha, Asish K., Patti, Mary-Elizabeth, Goldfine, Allison, Ruderman, Neil B., Gonzalez, Frank J., Kahn, C. Ronald
Published 2009

The evolution of insulin resistance in muscle of the glucose infused rat

by Brandon, Amanda E., Hoy, Andrew J., Wright, Lauren E., Turner, Nigel, Hegarty, Bronwyn D., Iseli, Tristan J., Xu, X. Julia, Cooney, Gregory J., Saha, Asish K., Ruderman, Neil B., Kraegen, Edward W.
Published 2011

Pregnancy Induces Resistance to the Anorectic Effect of Hypothalamic Malonyl-CoA and the Thermogenic Effect of Hypothalamic AMPK Inhibition in Female Rats

by Martínez de Morentin, Pablo B., Lage, Ricardo, González-García, Ismael, Ruíz-Pino, Francisco, Martins, Luís, Fernández-Mallo, Diana, Gallego, Rosalía, Fernø, Johan, Señarís, Rosa, Saha, Asish K., Tovar, Sulay, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Published in Endocrinology (2015)

SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase

by Laurent, Gaëlle, German, Natalie J, Saha, Asish K, de Boer, Vincent CJ, Fischer, Frank, Boanca, Gina, Dephoure, Noah, Vaitheesvaran, Bhavapriya, Davies, Michael, Gygi, Steven P, Muoio, Deborah M, Kurland, Irwin J, Steegborn, Clemens, Ruderman, Neil B, Haigis, Marcia C
Published 2012