Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle: Association With Changes in cAMP, Energy State, and Endogenous Fuel Mobilization

Por Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ruderman, Neil B.
Publicado em 2009

AMPK activation: a therapeutic target for type 2 diabetes?

Por Coughlan, Kimberly A, Valentine, Rudy J, Ruderman, Neil B, Saha, Asish K
Publicado em 2014

Insulin inhibits AMPK activity and phosphorylates AMPK Ser(485/491) through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

Por Valentine, Rudy J., Coughlan, Kimberly A., Ruderman, Neil B., Saha, Asish K.
Publicado no Arch Biochem Biophys (2014)

Nutrient Excess in AMPK Downregulation and Insulin Resistance

Por Coughlan, Kimberly A., Valentine, Rudy J., Ruderman, Neil B., Saha, Asish K.
Publicado no J Endocrinol Diabetes Obes (2013)

Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation?

Por Saha, Asish K, Xu, X. Julia, Balon, Thomas W, Brandon, Amanda, Kraegen, Edward W, Ruderman, Neil B
Publicado em 2011

AMPK and SIRT1: a long-standing partnership?

Por Ruderman, Neil B., Julia Xu, X., Nelson, Lauren, Cacicedo, José M., Saha, Asish K., Lan, Fan, Ido, Yasuo
Publicado em 2010

AMP-activated Protein Kinase Is Activated as a Consequence of Lipolysis in the Adipocyte: POTENTIAL MECHANISM AND PHYSIOLOGICAL RELEVANCE

Por Gauthier, Marie-Soleil, Miyoshi, Hideaki, Souza, Sandra C., Cacicedo, José M., Saha, Asish K., Greenberg, Andrew S., Ruderman, Neil B.
Publicado em 2008

Central Ghrelin Regulates Peripheral Lipid Metabolism in a Growth Hormone-Independent Fashion

Por Sangiao-Alvarellos, Susana, Vázquez, María J., Varela, Luis, Nogueiras, Rubén, Saha, Asish K., Cordido, Fernando, López, Miguel, Diéguez, Carlos
Publicado em 2009

Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender

Por Lage, Ricardo, Vázquez, María J., Varela, Luis, Saha, Asish K., Vidal-Puig, Antonio, Nogueiras, Rubén, Diéguez, Carlos, López, Miguel
Publicado em 2010

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle

Por Saha, Asish K., Xu, X. Julia, Lawson, Ebony, Deoliveira, Rosangela, Brandon, Amanda E., Kraegen, Edward W., Ruderman, Neil B.
Publicado em 2010

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells

Por Coughlan, Kimberly A., Valentine, Rudy J., Sudit, Bella S., Allen, Katherine, Dagon, Yossi, Kahn, Barbara B., Ruderman, Neil B., Saha, Asish K.
Publicado no J Biol Chem (2016)

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

Por Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Publicado em 2002

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

Por Suchankova, Gabriela, Nelson, Lauren E., Gerhart-Hines, Zachary, Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ido, Yasuo, Puigserver, Pere, Ruderman, Neil B.
Publicado em 2008

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Por Harriman, Geraldine, Greenwood, Jeremy, Bhat, Sathesh, Huang, Xinyi, Wang, Ruiying, Paul, Debamita, Tong, Liang, Saha, Asish K., Westlin, William F., Kapeller, Rosana, Harwood, H. James
Publicado no Proc Natl Acad Sci U S A (2016)

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

Por Ho, Linh, Titus, Allen Sam, Banerjee, Kushal Kr, George, Suji, Lin, Wei, Deota, Shaunak, Saha, Asish K., Nakamura, Ken, Gut, Philipp, Verdin, Eric, Kolthur-Seetharam, Ullas
Publicado em 2013

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats

Por Coughlan, Kimberly A., Balon, Thomas W., Valentine, Rudy J., Petrocelli, Robert, Schultz, Vera, Brandon, Amanda, Cooney, Gregory J., Kraegen, Edward W., Ruderman, Neil B., Saha, Asish K.
Publicado no PLoS One (2015)

Ablation of ARNT/HIF1β in Liver Alters Gluconeogenesis, Lipogenic Gene Expression, and Serum Ketones

Por Wang, Xiaohui L., Suzuki, Ryo, Lee, Kevin, Tran, Thien, Gunton, Jenny E., Saha, Asish K., Patti, Mary-Elizabeth, Goldfine, Allison, Ruderman, Neil B., Gonzalez, Frank J., Kahn, C. Ronald
Publicado em 2009

The evolution of insulin resistance in muscle of the glucose infused rat

Por Brandon, Amanda E., Hoy, Andrew J., Wright, Lauren E., Turner, Nigel, Hegarty, Bronwyn D., Iseli, Tristan J., Xu, X. Julia, Cooney, Gregory J., Saha, Asish K., Ruderman, Neil B., Kraegen, Edward W.
Publicado em 2011

Pregnancy Induces Resistance to the Anorectic Effect of Hypothalamic Malonyl-CoA and the Thermogenic Effect of Hypothalamic AMPK Inhibition in Female Rats

Por Martínez de Morentin, Pablo B., Lage, Ricardo, González-García, Ismael, Ruíz-Pino, Francisco, Martins, Luís, Fernández-Mallo, Diana, Gallego, Rosalía, Fernø, Johan, Señarís, Rosa, Saha, Asish K., Tovar, Sulay, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Publicado no Endocrinology (2015)

SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase

Por Laurent, Gaëlle, German, Natalie J, Saha, Asish K, de Boer, Vincent CJ, Fischer, Frank, Boanca, Gina, Dephoure, Noah, Vaitheesvaran, Bhavapriya, Davies, Michael, Gygi, Steven P, Muoio, Deborah M, Kurland, Irwin J, Steegborn, Clemens, Ruderman, Neil B, Haigis, Marcia C
Publicado em 2012