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Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle: Association With Changes in cAMP, Energy State, and Endogenous Fuel Mobilization

OBJECTIVE: Interleukin-6 (IL-6) directly activates AMP-activated protein kinase (AMPK) in vivo and in vitro; however, the mechanism by which it does so is unknown. RESEARCH DESIGN AND METHODS: We examined this question in skeletal muscle using an incubated rat extensor digitorum longus (EDL) muscle...

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Detalhes bibliográficos
Main Authors: Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ruderman, Neil B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731526/
https://ncbi.nlm.nih.gov/pubmed/19502419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1293
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