Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction

Por Kraegen, Edward W., Cooney, Gregory J., Turner, Nigel
Publicado em 2008

Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice.

Por Hoehn, Kyle L., Turner, Nigel, Cooney, Gregory J., James, David E.
Publicado em 2012

Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet

Por Turner, Nigel, Leslie, Simon J, Hallahan, Nicole L, Cooney, Gregory J
Publicado em 2012

PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis

Por Liu, Menghan, Montgomery, Magdalene K., Fiveash, Corrine E., Osborne, Brenna, Cooney, Gregory J., Bell-Anderson, Kim, Turner, Nigel
Publicado em 2014

Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis

Por Holt, Lowenna J., Lyons, Ruth J., Ryan, Ashleigh S., Beale, Susan M., Ward, Andrew, Cooney, Gregory J., Daly, Roger J.
Publicado em 2009

Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle

Por Montgomery, Magdalene K., Osborne, Brenna, Brown, Simon H. J., Small, Lewin, Mitchell, Todd W., Cooney, Gregory J., Turner, Nigel
Publicado em 2013

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

Por Hoy, Andrew J., Brandon, Amanda E., Turner, Nigel, Watt, Matthew J., Bruce, Clinton R., Cooney, Gregory J., Kraegen, Edward W.
Publicado em 2009

Minimal impact of age and housing temperature on the metabolic phenotype of Acc2(−/−) mice

Por Brandon, Amanda E, Stuart, Ella, Leslie, Simon J, Hoehn, Kyle L, James, David E, Kraegen, Edward W, Turner, Nigel, Cooney, Gregory J
Publicado no J Endocrinol (2015)

Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ

Por Iseli, Tristan J., Turner, Nigel, Zeng, Xiao-Yi, Cooney, Gregory J., Kraegen, Edward W., Yao, Sheng, Ye, Yang, James, David E., Ye, Ji-Ming
Publicado em 2013

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance

Por Bruce, Clinton R., Hoy, Andrew J., Turner, Nigel, Watt, Matthew J., Allen, Tamara L., Carpenter, Kevin, Cooney, Gregory J., Febbraio, Mark A., Kraegen, Edward W.
Publicado em 2009

PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle

Por Ye, Ji-Ming, Tid-Ang, Jennifer, Turner, Nigel, Zeng, Xiao-Yi, Li, Hai-Yan, Cooney, Gregory J, Wulff, Erik Max, Sauerberg, Per, Kraegen, Edward W
Publicado em 2011

Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance

Por Brandon, Amanda E., Tid-Ang, Jennifer, Wright, Lauren E., Stuart, Ella, Suryana, Eurwin, Bentley, Nicholas, Turner, Nigel, Cooney, Gregory J., Ruderman, Neil B., Kraegen, Edward W.
Publicado no PLoS One (2015)

Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle

Por Boden, Michael J., Brandon, Amanda E., Tid-Ang, Jennifer D., Preston, Elaine, Wilks, Donna, Stuart, Ella, Cleasby, Mark E., Turner, Nigel, Cooney, Gregory J., Kraegen, Edward W.
Publicado em 2012

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats

Por Coughlan, Kimberly A., Balon, Thomas W., Valentine, Rudy J., Petrocelli, Robert, Schultz, Vera, Brandon, Amanda, Cooney, Gregory J., Kraegen, Edward W., Ruderman, Neil B., Saha, Asish K.
Publicado no PLoS One (2015)

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

Por Nagarajan, Shilpa R., Brandon, Amanda E., McKenna, Jessie A., Shtein, Harrison C., Nguyen, Thinh Q., Suryana, Eurwin, Poronnik, Philip, Cooney, Gregory J., Saunders, Darren N., Hoy, Andrew J.
Publicado no PLoS One (2017)

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

Por Cooney, Gregory J, Lyons, Ruth J, Crew, A Jayne, Jensen, Thomas E, Molero, Juan Carlos, Mitchell, Christopher J, Biden, Trevor J, Ormandy, Christopher J, James, David E, Daly, Roger J
Publicado em 2004

Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance

Por Ren, Lu-Ping, Chan, Stanley M. H., Zeng, Xiao-Yi, Laybutt, D. Ross, Iseli, Tristan J., Sun, Ruo-Qiong, Kraegen, Edward W., Cooney, Gregory J., Turner, Nigel, Ye, Ji-Ming
Publicado em 2012

The evolution of insulin resistance in muscle of the glucose infused rat

Por Brandon, Amanda E., Hoy, Andrew J., Wright, Lauren E., Turner, Nigel, Hegarty, Bronwyn D., Iseli, Tristan J., Xu, X. Julia, Cooney, Gregory J., Saha, Asish K., Ruderman, Neil B., Kraegen, Edward W.
Publicado em 2011

Mice with a Disruption of the Imprinted Grb10 Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life

Por Smith, Florentia M., Holt, Lowenna J., Garfield, Alastair S., Charalambous, Marika, Koumanov, Francoise, Perry, Mark, Bazzani, Reto, Sheardown, Steven A., Hegarty, Bronwyn D., Lyons, Ruth J., Cooney, Gregory J., Daly, Roger J., Ward, Andrew
Publicado em 2007

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

Por Turner, Nigel, Hariharan, Krit, TidAng, Jennifer, Frangioudakis, Georgia, Beale, Susan M., Wright, Lauren E., Zeng, Xiao Yi, Leslie, Simon J., Li, Jing-Ya, Kraegen, Edward W., Cooney, Gregory J., Ye, Ji-Ming
Publicado em 2009