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Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice
Gene targeting was used to characterize the physiological role of growth factor receptor-bound (Grb)14, an adapter-type signalling protein that associates with the insulin receptor (IR). Adult male Grb14(−/−) mice displayed improved glucose tolerance, lower circulating insulin levels, and increased...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271812/ https://ncbi.nlm.nih.gov/pubmed/14749734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600082 |
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