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Structural Basis for Inhibition of the Insulin Receptor by the Adaptor Protein Grb14
Grb14, a member of the Grb7 adaptor protein family, possesses a pleckstrin homology (PH) domain, a C-terminal Src homology-2 (SH2) domain, and an intervening stretch of ~45 residues known as the BPS region, which is unique to this adaptor family. Previous studies have demonstrated that Grb14 is a ti...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526137/ https://ncbi.nlm.nih.gov/pubmed/16246733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.09.001 |
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