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PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle

BACKGROUND AND PURPOSE: The peroxisome proliferator-activated receptor (PPAR)δ has been considered a therapeutic target for diabetes and obesity through enhancement of fatty acid oxidation. The present study aimed to characterize the effects of PPARδ agonists during insulin resistance of the whole b...

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Main Authors: Ye, Ji-Ming, Tid-Ang, Jennifer, Turner, Nigel, Zeng, Xiao-Yi, Li, Hai-Yan, Cooney, Gregory J, Wulff, Erik Max, Sauerberg, Per, Kraegen, Edward W
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101618/
https://ncbi.nlm.nih.gov/pubmed/21265823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01240.x
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