Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ(−/−), PPARδ(−/−), PPARγδ(−/−), or LXRαβ(−/−) bone marrow

Macrophage lipid metabolism and inflammatory responses are both regulated by the nuclear receptors PPAR and LXR. Emerging links between inflammation and metabolic disease progression suggest that PPAR and LXR signaling may alter macrophage function and thereby impact systemic metabolism. In this stu...

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Bibliographic Details
Main Authors: Marathe, Chaitra, Bradley, Michelle N., Hong, Cynthia, Chao, Lily, Wilpitz, Damien, Salazar, Jon, Tontonoz, Peter
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636915/
https://ncbi.nlm.nih.gov/pubmed/18772483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800189-JLR200
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