Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo lipogenesis (DNL) compared to extrahepatic lipid...

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Autors principals: Ren, Lu-Ping, Chan, Stanley M. H., Zeng, Xiao-Yi, Laybutt, D. Ross, Iseli, Tristan J., Sun, Ruo-Qiong, Kraegen, Edward W., Cooney, Gregory J., Turner, Nigel, Ye, Ji-Ming
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280252/
https://ncbi.nlm.nih.gov/pubmed/22355328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030816
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