Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo lipogenesis (DNL) compared to extrahepatic lipid...

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Main Authors: Ren, Lu-Ping, Chan, Stanley M. H., Zeng, Xiao-Yi, Laybutt, D. Ross, Iseli, Tristan J., Sun, Ruo-Qiong, Kraegen, Edward W., Cooney, Gregory J., Turner, Nigel, Ye, Ji-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280252/
https://ncbi.nlm.nih.gov/pubmed/22355328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030816
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