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Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy

BACKGROUND: When stressed, eukaryotic cells produce triacylglycerol (TAG) to store nutrients and mobilize autophagy to combat internal damage. We and others previously reported that in yeast, elimination of TAG synthesizing enzymes inhibits autophagy under nitrogen starvation, yet the underlying mec...

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Dades bibliogràfiques
Publicat a:BMC Biol
Autors principals: Li, Dan, Yang, Shu-Gao, He, Cheng-Wen, Zhang, Zheng-Tan, Liang, Yongheng, Li, Hui, Zhu, Jing, Su, Xiong, Gong, Qingqiu, Xie, Zhiping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453538/
https://ncbi.nlm.nih.gov/pubmed/32859196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00837-w
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