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Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy
BACKGROUND: When stressed, eukaryotic cells produce triacylglycerol (TAG) to store nutrients and mobilize autophagy to combat internal damage. We and others previously reported that in yeast, elimination of TAG synthesizing enzymes inhibits autophagy under nitrogen starvation, yet the underlying mec...
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| Publicado no: | BMC Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7453538/ https://ncbi.nlm.nih.gov/pubmed/32859196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00837-w |
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