Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy

BACKGROUND: When stressed, eukaryotic cells produce triacylglycerol (TAG) to store nutrients and mobilize autophagy to combat internal damage. We and others previously reported that in yeast, elimination of TAG synthesizing enzymes inhibits autophagy under nitrogen starvation, yet the underlying mec...

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Vydáno v:BMC Biol
Hlavní autoři: Li, Dan, Yang, Shu-Gao, He, Cheng-Wen, Zhang, Zheng-Tan, Liang, Yongheng, Li, Hui, Zhu, Jing, Su, Xiong, Gong, Qingqiu, Xie, Zhiping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453538/
https://ncbi.nlm.nih.gov/pubmed/32859196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00837-w
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