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Asbestos-induced Disruption of Calcium Homeostasis Induces Endoplasmic Reticulum Stress in Macrophages

Although the mechanisms for fibrosis development remain largely unknown, recent evidence indicates that endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) may act as an important fibrotic stimulus in diseased lungs. ER stress is observed in lungs of patients with...

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Publicado en:J Biol Chem
Autores principales: Ryan, Alan J., Larson-Casey, Jennifer L., He, Chao, Murthy, Shuhba, Carter, A. Brent
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246095/
https://ncbi.nlm.nih.gov/pubmed/25324550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579870
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