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Production of Infectious Human Cytomegalovirus Virions Is Inhibited by Drugs That Disrupt Calcium Homeostasis in the Endoplasmic Reticulum

We previously reported that human cytomegalovirus (HCMV) infection induces endoplasmic reticulum (ER) stress, resulting in activation of the unfolded protein response (UPR). Although some normal consequences of UPR activation (e.g., translation attenuation) are detrimental to viral infection, we hav...

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Detalhes bibliográficos
Main Authors: Isler, Jennifer A., Maguire, Tobi Goldberg, Alwine, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316032/
https://ncbi.nlm.nih.gov/pubmed/16306610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15388-15397.2005
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