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The Endoplasmic Reticulum Chaperone BiP/GRP78 Is Important in the Structure and Function of the Human Cytomegalovirus Assembly Compartment

We previously demonstrated that the endoplasmic reticulum (ER) chaperone BiP functions in human cytomegalovirus (HCMV) assembly and egress. Here, we show that BiP localizes in two cytoplasmic structures in infected cells. Antibodies to the extreme C terminus, which includes BiP's KDEL ER locali...

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Main Authors: Buchkovich, Nicholas J., Maguire, Tobi G., Paton, Adrienne W., Paton, James C., Alwine, James C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772683/
https://ncbi.nlm.nih.gov/pubmed/19741001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00762-09
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