Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis

Lung cancer is the leading cause of cancer mortality worldwide and KRAS is the most commonly mutated gene in lung adenocarcinoma (LUAD). The 78-kDa glucose-regulated protein GRP78/BiP is a key endoplasmic reticulum (ER) chaperone protein and a major pro-survival effector of the unfolded protein resp...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncogene
Hlavní autoři: Rangel, Daisy Flores, Dubeau, Louis, Park, Ryan, Chan, Priscilla, Ha, Dat P., Pulido, Mario A., Mullen, Daniel J., Vorobyova, Ivetta, Zhou, Beiyun, Borok, Zea, Offringa, Ite A., Lee, Amy S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179725/
https://ncbi.nlm.nih.gov/pubmed/33931739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01791-9
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky