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Human Cytomegalovirus Induces the Endoplasmic Reticulum Chaperone BiP through Increased Transcription and Activation of Translation by Using the BiP Internal Ribosome Entry Site

The endoplasmic reticulum (ER) chaperone BiP (immunoglobulin binding protein) plays a major role in the control of the unfolded protein response. We have previously shown that BiP levels are dramatically increased during human cytomegalovirus (HCMV) infection, where BiP performs unique roles in vira...

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Autors principals: Buchkovich, Nicholas J., Yu, Yongjun, Pierciey, Francis J., Alwine, James C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953172/
https://ncbi.nlm.nih.gov/pubmed/20739513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01330-10
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