Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo lipogenesis (DNL) compared to extrahepatic lipid...

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Autori principali: Ren, Lu-Ping, Chan, Stanley M. H., Zeng, Xiao-Yi, Laybutt, D. Ross, Iseli, Tristan J., Sun, Ruo-Qiong, Kraegen, Edward W., Cooney, Gregory J., Turner, Nigel, Ye, Ji-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280252/
https://ncbi.nlm.nih.gov/pubmed/22355328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030816
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