A metabolic prosurvival role for PML in breast cancer

Cancer cells exhibit an aberrant metabolism that facilitates more efficient production of biomass and hence tumor growth and progression. However, the genetic cues modulating this metabolic switch remain largely undetermined. We identified a metabolic function for the promyelocytic leukemia (PML) ge...

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Main Authors: Carracedo, Arkaitz, Weiss, Dror, Leliaert, Amy K., Bhasin, Manoj, de Boer, Vincent C.J., Laurent, Gaelle, Adams, Andrew C., Sundvall, Maria, Song, Su Jung, Ito, Keisuke, Finley, Lydia S., Egia, Ainara, Libermann, Towia, Gerhart-Hines, Zachary, Puigserver, Pere, Haigis, Marcia C., Maratos-Flier, Elefteria, Richardson, Andrea L., Schafer, Zachary T., Pandolfi, Pier P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433768/
https://ncbi.nlm.nih.gov/pubmed/22886304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62129
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