A metabolic prosurvival role for PML in breast cancer

Cancer cells exhibit an aberrant metabolism that facilitates more efficient production of biomass and hence tumor growth and progression. However, the genetic cues modulating this metabolic switch remain largely undetermined. We identified a metabolic function for the promyelocytic leukemia (PML) ge...

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Detalhes bibliográficos
Main Authors: Carracedo, Arkaitz, Weiss, Dror, Leliaert, Amy K., Bhasin, Manoj, de Boer, Vincent C.J., Laurent, Gaelle, Adams, Andrew C., Sundvall, Maria, Song, Su Jung, Ito, Keisuke, Finley, Lydia S., Egia, Ainara, Libermann, Towia, Gerhart-Hines, Zachary, Puigserver, Pere, Haigis, Marcia C., Maratos-Flier, Elefteria, Richardson, Andrea L., Schafer, Zachary T., Pandolfi, Pier P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433768/
https://ncbi.nlm.nih.gov/pubmed/22886304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62129
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