A metabolic prosurvival role for PML in breast cancer

Cancer cells exhibit an aberrant metabolism that facilitates more efficient production of biomass and hence tumor growth and progression. However, the genetic cues modulating this metabolic switch remain largely undetermined. We identified a metabolic function for the promyelocytic leukemia (PML) ge...

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Библиографические подробности
Главные авторы: Carracedo, Arkaitz, Weiss, Dror, Leliaert, Amy K., Bhasin, Manoj, de Boer, Vincent C.J., Laurent, Gaelle, Adams, Andrew C., Sundvall, Maria, Song, Su Jung, Ito, Keisuke, Finley, Lydia S., Egia, Ainara, Libermann, Towia, Gerhart-Hines, Zachary, Puigserver, Pere, Haigis, Marcia C., Maratos-Flier, Elefteria, Richardson, Andrea L., Schafer, Zachary T., Pandolfi, Pier P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433768/
https://ncbi.nlm.nih.gov/pubmed/22886304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62129
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