ロード中...
Pml represses tumour progression through inhibition of mTOR
The promyelocytic leukaemia gene PML is a pleiotropic tumour suppressor. We have recently demonstrated that PML opposes mTOR-HIF1α-VEGF signalling in hypoxia. To determine the relevance of PML-mTOR antagonism in tumourigenesis, we have intercrossed Pml null mice with Tsc2 heterozygous mice, which de...
保存先:
| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
WILEY-VCH Verlag
2011
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123467/ https://ncbi.nlm.nih.gov/pubmed/21387562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100130 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|