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Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression

The promyelocytic leukemia (PML) tumor suppressor gene was initially identified as part of the t(15:17) chromosomal translocation associated with acute promyelocytic leukemia (APL). The PML protein is responsible for the assembly and function of characteristic nuclear domains known as PML-nuclear bo...

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Hlavní autoři: Papa, Antonella, Cordon-Cardo, Carlos, Bernardi, Rosa, Pandolfi, Pier Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591099/
https://ncbi.nlm.nih.gov/pubmed/23486996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912473604
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