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Role of Promyelocytic Leukemia (Pml) Protein in Tumor Suppression

The promyelocytic leukemia (PML) gene encodes a putative tumor suppressor gene involved in the control of apoptosis, which is fused to the retinoic acid receptor α (RARα) gene in the vast majority of acute promyelocytic leukemia (APL) patients as a consequence of chromosomal translocations. The PMLR...

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Detalhes bibliográficos
Main Authors: Rego, Eduardo M., Wang, Zhu-Gang, Peruzzi, Daniela, He, Le-Zhen, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195907/
https://ncbi.nlm.nih.gov/pubmed/11181703
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