The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage

The promyelocytic leukemia (PML) gene, a tumor suppressor inactivated in acute promyelocytic leukemia (APL), regulates apoptosis induced by DNA damage. However, the molecular mechanisms by which PML modulates apoptosis following genotoxic stress are only partially elucidated. PML is essential for p5...

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Autors principals: Salomoni, Paolo, Bernardi, Rosa, Bergmann, Stephan, Changou, Austin, Tuttle, Sara, Pandolfi, Pier Paolo
Format: Artigo
Idioma:Inglês
Publicat: © 2005 by The American Society of Hematology 2005
Matèries:
Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895009/
https://ncbi.nlm.nih.gov/pubmed/15626733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3782
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