The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage

The promyelocytic leukemia (PML) gene, a tumor suppressor inactivated in acute promyelocytic leukemia (APL), regulates apoptosis induced by DNA damage. However, the molecular mechanisms by which PML modulates apoptosis following genotoxic stress are only partially elucidated. PML is essential for p5...

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Detalhes bibliográficos
Main Authors: Salomoni, Paolo, Bernardi, Rosa, Bergmann, Stephan, Changou, Austin, Tuttle, Sara, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895009/
https://ncbi.nlm.nih.gov/pubmed/15626733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3782
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