The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage

The promyelocytic leukemia (PML) gene, a tumor suppressor inactivated in acute promyelocytic leukemia (APL), regulates apoptosis induced by DNA damage. However, the molecular mechanisms by which PML modulates apoptosis following genotoxic stress are only partially elucidated. PML is essential for p5...

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Bibliografiske detaljer
Main Authors: Salomoni, Paolo, Bernardi, Rosa, Bergmann, Stephan, Changou, Austin, Tuttle, Sara, Pandolfi, Pier Paolo
Format: Artigo
Sprog:Inglês
Udgivet: © 2005 by The American Society of Hematology 2005
Fag:
Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895009/
https://ncbi.nlm.nih.gov/pubmed/15626733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3782
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