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Promyelocytic Leukemia Protein (Pml) and Daxx Participate in a Novel Nuclear Pathway for Apoptosis

The promyelocytic leukemia protein (PML) gene of acute promyelocytic leukemia (APL) encodes a cell growth and tumor suppressor essential for multiple apoptotic signals. Daxx was identified as a molecule important for the cytoplasmic transduction of the Fas proapoptotic stimulus. Here, we show that u...

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Autori principali: Zhong, Sue, Salomoni, Paolo, Ronchetti, Simona, Guo, Ailan, Ruggero, Davide, Pandolfi, Pier Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195846/
https://ncbi.nlm.nih.gov/pubmed/10684855
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