Impact of the ICAL on the treatment of acute leukemia

le Rego, Eduardo M.
Foilsithe in Blood Adv (2017)

Modeling dynamics and alternative treatment strategies in acute promyelocytic leukemia

le Yoshinari, Gerson Hiroshi, Fassoni, Artur César, Mello, Luis Fernando, Rego, Eduardo M.
Foilsithe in PLoS One (2019)

Retinoic acid (RA) and As(2)O(3) treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RAR...

le Rego, Eduardo M., He, Li-Zhen, Warrell, Raymond P., Wang, Zhu-Gang, Pandolfi, Pier Paolo
Foilsithe 2000

Role of Promyelocytic Leukemia (Pml) Protein in Tumor Suppression

le Rego, Eduardo M., Wang, Zhu-Gang, Peruzzi, Daniela, He, Le-Zhen, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Foilsithe 2001

In vivo analysis of the role of aberrant histone deacetylase recruitment and RARα blockade in the pathogenesis of acute promyelocytic leukemia

le Matsushita, Hiromichi, Scaglioni, Pier Paolo, Bhaumik, Mantu, Rego, Eduardo M., Cai, Lu Fan, Majid, Samia M., Miyachi, Hayato, Kakizuka, Akira, Miller, Wilson H., Pandolfi, Pier Paolo
Foilsithe 2006

Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience

le da Silva, Wellington Fernandes, da Rosa, Lidiane Inês, Seguro, Fernanda Salles, Silveira, Douglas Rafaele Almeida, Bendit, Israel, Buccheri, Valeria, Velloso, Elvira Deolinda Rodrigues Pereira, Rocha, Vanderson, Rego, Eduardo M
Foilsithe in Clinics (Sao Paulo) (2020)

Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia

le Oliveira, Lucila H, Schiavinato, Josiane L, Fráguas, Mariane S, Lucena-Araujo, Antonio R, Haddad, Rodrigo, Araújo, Amélia G, Dalmazzo, Leandro F, Rego, Eduardo M, Covas, Dimas T, Zago, Marco A, Panepucci, Rodrigo A
Foilsithe in Cancer Sci (2015)

Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia

le Bezerra, Matheus F., Coelho-Silva, Juan L, Nascimento, Jessica C., Benicio, Mariana T., Rocha, Cintia R., Machado, Cintia G., Rego, Eduardo M., Bezerra, Marcos A., Lucena-Araujo, Antonio R., Beltrão, Eduardo I.
Foilsithe in Haematologica (2017)

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

le Guibal, Florence C., Alberich-Jorda, Meritxell, Hirai, Hideyo, Ebralidze, Alexander, Levantini, Elena, Di Ruscio, Annalisa, Zhang, Pu, Santana-Lemos, Barbara A., Neuberg, Donna, Wagers, Amy J., Rego, Eduardo M., Tenen, Daniel G.
Foilsithe 2009

Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia

le Gimenes-Teixeira, Hamilton L, Lucena-Araujo, Antonio R, dos Santos, Guilherme A, Zanette, Dalila L, Scheucher, Priscila S, Oliveira, Luciana C, Dalmazzo, Leandro F, Silva-Júnior, Wilson A, Falcão, Roberto P, Rego, Eduardo M
Foilsithe 2013

Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome

le Coelho-Silva, Juan L., Silveira, Douglas R. A., Pereira-Martins, Diego A., Rojas, Cesar A. O., Lucena-Araujo, Antonio R., Rego, Eduardo M., Machado-Neto, João A., Bendit, Israel, Rocha, Vanderson, Traina, Fabiola
Foilsithe in Sci Rep (2021)

The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia

le Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Pereira-Martins, Diego Antonio, Augusto dos Santos, Guilherme, Almeida-Silveira, Douglas R., Weinhäuser, Isabel, Antônio de Souza, Gustavo, Houtsma, Roos, Schuringa, Jan Jacob, Rego, Eduardo M., Faça, Vitor M.
Foilsithe in Mol Cell Proteomics (2021)

Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model

le Assis, Patricia A., De Figueiredo-Pontes, Lorena L., Lima, Ana Silvia G., Leão, Vitor, Cândido, Larissa A., Pintão, Carolina T., Garcia, Aglair B., Saggioro, Fabiano P., Panepucci, Rodrigo A, Chahud, Fernando, Nagler, Arnon, Falcão, Roberto P., Rego, Eduardo M.
Foilsithe in J Exp Clin Cancer Res (2015)

MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model

le Pereira-Martins, Diego A., Weinhäuser, Isabel, Coelho-Silva, Juan Luiz, França-Neto, Pedro L., Almeida, Luciana Y., Bianco, Thiago M., Silva, Cleide L., França, Rafael F., Traina, Fabiola, Rego, Eduardo M., Schuringa, Jan Jacob, Lucena-Araujo, Antonio R.
Foilsithe in Cell Death Dis (2021)

Halofuginone Has Anti-Proliferative Effects in Acute Promyelocytic Leukemia by Modulating the Transforming Growth Factor Beta Signaling Pathway

le de Figueiredo-Pontes, Lorena L., Assis, Patricia A., Santana-Lemos, Bárbara A. A., Jácomo, Rafael H., Lima, Ana Sílvia G., Garcia, Aglair B., Thomé, Carolina H., Araújo, Amélia G., Panepucci, Rodrigo A., Zago, Marco A., Nagler, Arnon, Falcão, Roberto P., Rego, Eduardo M.
Foilsithe 2011

Linker for Activation of T-cell Family Member2 (LAT2) a Lipid Raft Adaptor Protein for AKT Signaling, Is an Early Mediator of Alkylphospholipid Anti-leukemic Activity

le Thomé, Carolina H., dos Santos, Guilherme A., Ferreira, Germano A., Scheucher, Priscila S., Izumi, Clarice, Leopoldino, Andreia M., Simão, Ana Maria, Ciancaglini, Pietro, de Oliveira, Kleber T., Chin, Alice, Hanash, Samir M., Falcão, Roberto P., Rego, Eduardo M., Greene, Lewis J., Faça, Vitor M.
Foilsithe 2012

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype

le Lucena-Araujo, Antonio R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Thomé, Carolina, Scheucher, Priscila S., Lange, Ana P., Paiva, Helder H., Hemmelgarn, Benjamin T., Morais-Sobral, Mariana C., Azevedo, Elisa A., Franca-Neto, Pedro L., Franca, Rafael F., Silva, Cleide L., Krause, Alexandre, Rego, Eduardo M.
Foilsithe in Oncotarget (2016)

Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia

le Silveira, Douglas R. A., Quek, Lynn, Santos, Itamar S., Corby, Anna, Coelho-Silva, Juan L., Pereira-Martins, Diego A., Vallance, Grant, Brown, Benjamin, Nardinelli, Luciana, Silva, Wellington F., Velloso, Elvira D. R. P., Lucena-Araujo, Antonio R., Traina, Fabiola, Peniket, Andy, Vyas, Paresh, Rego, Eduardo M., Bendit, Israel, Rocha, Vanderson
Foilsithe in Blood Adv (2020)

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

le Wei, Shuo, Kozono, Shingo, Kats, Lev, Nechama, Morris, Li, Wenzong, Guarnerio, Jlenia, Luo, Manli, You, Mi-Hyeon, Yao, Yandan, Kondo, Asami, Hu, Hai, Bozkurt, Gunes, Moerke, Nathan J., Cao, Shugeng, Reschke, Markus, Chen, Chun-Hau, Rego, Eduardo M., LoCoco, Francesco, Cantley, Lewis, Lee, Tae Ho, Wu, Hao, Zhang, Yan, Pandolfi, Pier Paolo, Zhou, Xiao Zhen, Lu, Kun Ping
Foilsithe in Nat Med (2015)

High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

le Lucena-Araujo, Antonio R., Kim, Haesook T., Thomé, Carolina, Jacomo, Rafael H., Melo, Raul A., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Glória, Ana Beatriz F., Chauffaille, Maria de Lourdes, Athayde, Melina, Chiattone, Carlos S., Mito, Ingrid, Bendlin, Rodrigo, Souza, Carmino, Bortolheiro, Cristina, Coelho-Silva, Juan L., Schrier, Stanley L., Tallman, Martin S., Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, Sanz, Miguel A., Rego, Eduardo M.
Foilsithe in Blood (2015)