SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate life span, control the onset of numerous age-associated diseases, and mediate metabolic homeostasis. We have uncovered a novel role for the mitochondrial sirtuin SIRT4 in the regulation of hepatic li...

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Detalhes bibliográficos
Main Authors: Laurent, Gaëlle, de Boer, Vincent C. J., Finley, Lydia W. S., Sweeney, Meredith, Lu, Hong, Schug, Thaddeus T., Cen, Yana, Jeong, Seung Min, Li, Xiaoling, Sauve, Anthony A., Haigis, Marcia C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838178/
https://ncbi.nlm.nih.gov/pubmed/24043310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00087-13
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