Membrane bending is critical for the stability of voltage sensor segments in the membrane

Por Callenberg, Keith M., Latorraca, Naomi R., Grabe, Michael
Publicado em 2012

Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations

Por Hertig, Samuel, Latorraca, Naomi R., Dror, Ron O.
Publicado no PLoS Comput Biol (2016)

Continuum Approaches to Understanding Ion and Peptide Interactions with the Membrane

Por Latorraca, Naomi R., Callenberg, Keith M., Boyle, Jon P., Grabe, Michael
Publicado em 2014

Mechanism of substrate translocation in an alternating access transporter

Por Latorraca, Naomi R., Fastman, Nathan M., Venkatakrishnan, A. J., Frommer, Wolf B., Dror, Ron O., Feng, Liang
Publicado no Cell (2017)

Catalytic activation of β-arrestin by GPCRs

Por Eichel, Kelsie, Jullié, Damien, Barsi-Rhyne, Benjamin, Latorraca, Naomi R., Masureel, Matthieu, Sibarita, Jean-Baptiste, Dror, Ron O., von Zastrow, Mark
Publicado no Nature (2018)

G(i)- and G(s)-coupled GPCRs show different modes of G-protein binding

Por Van Eps, Ned, Altenbach, Christian, Caro, Lydia N., Latorraca, Naomi R., Hollingsworth, Scott A., Dror, Ron O., Ernst, Oliver P., Hubbell, Wayne L.
Publicado no Proc Natl Acad Sci U S A (2018)

Diverse GPCRs exhibit conserved water networks for stabilization and activation

Por Venkatakrishnan, A. J., Ma, Anthony K., Fonseca, Rasmus, Latorraca, Naomi R., Kelly, Brendan, Betz, Robin M., Asawa, Chaitanya, Kobilka, Brian K., Dror, Ron O.
Publicado no Proc Natl Acad Sci U S A (2019)

Molecular mechanism of GPCR-mediated arrestin activation

Por Latorraca, Naomi R., Wang, Jason K., Bauer, Brian, Townshend, Raphael J. L., Hollingsworth, Scott A., Olivieri, Julia E., Xu, H. Eric, Sommer, Martha E., Dror, Ron O.
Publicado no Nature (2018)

Mechanism of intracellular allosteric β(2)AR antagonist revealed by X-ray crystal structure

Por Liu, Xiangyu, Ahn, Seungkirl, Kahsai, Alem W., Meng, Kai-Cheng, Latorraca, Naomi R., Pani, Biswaranjan, Venkatakrishnan, A. J., Masoudi, Ali, Weis, William I., Dror, Ron O., Chen, Xin, Lefkowitz, Robert J., Kobilka, Brian K.
Publicado no Nature (2017)

Structure of the μ Opioid Receptor-G(i) Protein Complex

Por Koehl, Antoine, Hu, Hongli, Maeda, Shoji, Zhang, Yan, Qu, Qianhui, Paggi, Joseph M., Latorraca, Naomi R., Hilger, Daniel, Dawson, Roger, Matile, Hugues, Schertler, Gebhard F. X., Granier, Sebastien, Weis, William I., Dror, Ron O., Manglik, Aashish, Skiniotis, Georgios, Kobilka, Brian K.
Publicado no Nature (2018)

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Por Kumar, Kaavya Krishna, Shalev-Benami, Moran, Robertson, Michael J., Hu, Hongli, Banister, Samuel D., Hollingsworth, Scott A., Latorraca, Naomi R., Kato, Hideaki E., Hilger, Daniel, Maeda, Shoji, Weis, William I., Farrens, David L., Dror, Ron O., Malhotra, Sanjay V., Kobilka, Brian K., Skiniotis, Georgios
Publicado no Cell (2019)

Identification of Phosphorylation Codes for Arrestin Recruitment by G protein-Coupled Receptors

Por Zhou, X. Edward, He, Yuanzheng, de Waal, Parker W., Gao, Xiang, Kang, Yanyong, Van Eps, Ned, Yin, Yanting, Pal, Kuntal, Goswami, Devrishi, White, Thomas A., Barty, Anton, Latorraca, Naomi R., Chapman, Henry N., Hubbell, Wayne L., Dror, Ron O., Stevens, Raymond C., Cherezov, Vadim, Gurevich, Vsevolod V., Griffin, Patrick R., Ernst, Oliver P., Melcher, Karsten, Xu, H. Eric
Publicado no Cell (2017)