The cryo-electron microscopy structure of γ-Secretase: towards complex assembly, substrate recognition and a catalytic mechanism

od Kang, Yanyong, Melcher, Karsten, Xu, H. Eric
Wydane w Natl Sci Rev (2015)

A structural snapshot of the rhodopsin–arrestin complex

od Kang, Yanyong, Gao, Xiang, Zhou, X. Edward, He, Yuanzheng, Melcher, Karsten, Xu, H. Eric
Wydane w FEBS J (2015)

Alzheimer’s disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aβ42/Aβ40 ratio

od Xu, Ting-Hai, Yan, Yan, Kang, Yanyong, Jiang, Yi, Melcher, Karsten, Xu, H Eric
Wydane w Cell Discov (2016)

Structural study of TTR-52 reveals the mechanism by which a bridging molecule mediates apoptotic cell engulfment

od Kang, Yanyong, Zhao, Dongfeng, Liang, Huanhuan, Liu, Bin, Zhang, Yan, Liu, Qinwen, Wang, Xiaochen, Liu, Yingfang
Wydane 2012

Structure of a PLS-class Pentatricopeptide Repeat Protein Provides Insights into Mechanism of RNA Recognition

od Ban, Ting, Ke, Jiyuan, Chen, Runze, Gu, Xin, Tan, M. H. Eileen, Zhou, X. Edward, Kang, Yanyong, Melcher, Karsten, Zhu, Jian-Kang, Xu, H. Eric
Wydane 2013

Development of “plug and play” fiducial marks for structural studies of GPCR signaling complexes by single particle cryo-EM

od Dutka, Przemyslaw, Mukherjee, Somnath, Gao, Xiang, Kang, Yanyong, de Waal, Parker W., Wang, Lei, Zhuang, Youwen, Melcher, Karsten, Zhang, Cheng, Xu, H. Eric, Kossiakoff, Anthony A.
Wydane w Structure (2019)

Structure of formylpeptide receptor 2-G(i) complex reveals insights into ligand recognition and signaling

od Zhuang, Youwen, Liu, Heng, Edward Zhou, X., Kumar Verma, Ravi, de Waal, Parker W., Jang, Wonjo, Xu, Ting-Hai, Wang, Lei, Meng, Xing, Zhao, Gongpu, Kang, Yanyong, Melcher, Karsten, Fan, Hao, Lambert, Nevin A., Eric Xu, H., Zhang, Cheng
Wydane w Nat Commun (2020)

Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins

od Mukherjee, Somnath, Erramilli, Satchal K., Ammirati, Mark, Alvarez, Frances J. D., Fennell, Kimberly F., Purdy, Michael D., Skrobek, Blazej M., Radziwon, Katarzyna, Coukos, John, Kang, Yanyong, Dutka, Przemysław, Gao, Xiang, Qiu, Xiayang, Yeager, Mark, Eric Xu, H., Han, Seungil, Kossiakoff, Anthony A.
Wydane w Nat Commun (2020)

Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3

od Zhao, Li-Hua, Zhou, X Edward, Yi, Wei, Wu, Zhongshan, Liu, Yue, Kang, Yanyong, Hou, Li, de Waal, Parker W, Li, Suling, Jiang, Yi, Scaffidi, Adrian, Flematti, Gavin R, Smith, Steven M, Lam, Vinh Q, Griffin, Patrick R, Wang, Yonghong, Li, Jiayang, Melcher, Karsten, Xu, H Eric
Wydane w Cell Res (2015)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

od Kang, Yanyong, Kuybeda, Oleg, de Waal, Parker W., Mukherjee, Somnath, Van Eps, Ned, Dutka, Przemyslaw, Zhou, X. Edward, Bartesaghi, Alberto, Erramilli, Satchal, Morizumi, Takefumi, Gu, Xin, Yin, Yanting, Liu, Ping, Jiang, Yi, Meng, Xing, Zhao, Gongpu, Melcher, Karsten, Ernst, Oliver P., Kossiakoff, Anthony A., Subramaniam, Sriram, Xu, H. Eric
Wydane w Nature (2018)

Identification of Phosphorylation Codes for Arrestin Recruitment by G protein-Coupled Receptors

od Zhou, X. Edward, He, Yuanzheng, de Waal, Parker W., Gao, Xiang, Kang, Yanyong, Van Eps, Ned, Yin, Yanting, Pal, Kuntal, Goswami, Devrishi, White, Thomas A., Barty, Anton, Latorraca, Naomi R., Chapman, Henry N., Hubbell, Wayne L., Dror, Ron O., Stevens, Raymond C., Cherezov, Vadim, Gurevich, Vsevolod V., Griffin, Patrick R., Ernst, Oliver P., Melcher, Karsten, Xu, H. Eric
Wydane w Cell (2017)

Structure and dynamics of the active human parathyroid hormone receptor-1

od Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X. Edward, de Waal, Parker W., Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J., Jean-Alphonse, Frederic G., White, Alex D., Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J., Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H. Eric, Zhang, Yan
Wydane w Science (2019)

X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

od Zhou, X. Edward, Gao, Xiang, Barty, Anton, Kang, Yanyong, He, Yuanzheng, Liu, Wei, Ishchenko, Andrii, White, Thomas A., Yefanov, Oleksandr, Han, Gye Won, Xu, Qingping, de Waal, Parker W., Suino-Powell, Kelly M., Boutet, Sébastien, Williams, Garth J., Wang, Meitian, Li, Dianfan, Caffrey, Martin, Chapman, Henry N., Spence, John C.H., Fromme, Petra, Weierstall, Uwe, Stevens, Raymond C., Cherezov, Vadim, Melcher, Karsten, Xu, H. Eric
Wydane w Sci Data (2016)

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

od Kang, Yanyong, Zhou, X. Edward, Gao, Xiang, He, Yuanzheng, Liu, Wei, Ishchenko, Andrii, Barty, Anton, White, Thomas A., Yefanov, Oleksandr, Han, Gye Won, Xu, Qingping, de Waal, Parker W., Ke, Jiyuan, Eileen Tan, M. H., Zhang, Chenghai, Moeller, Arne, West, Graham M., Pascal, Bruce, Van Eps, Ned, Caro, Lydia N., Vishnivetskiy, Sergey A., Lee, Regina J., Suino-Powell, Kelly M., Gu, Xin, Pal, Kuntal, Ma, Jinming, Zhi, Xiaoyong, Boutet, Sébastien, Williams, Garth J., Messerschmidt, Marc, Gati, Cornelius, Zatsepin, Nadia A., Wang, Dingjie, James, Daniel, Basu, Shibom, Roy-Chowdhury, Shatabdi, Conrad, Chelsie, Coe, Jesse, Liu, Haiguang, Lisova, Stella, Kupitz, Christopher, Grotjohann, Ingo, Fromme, Raimund, Jiang, Yi, Tan, Minjia, Yang, Huaiyu, Li, Jun, Wang, Meitian, Zheng, Zhong, Li, Dianfan, Howe, Nicole, Zhao, Yingming, Standfuss, Jörg, Diederichs, Kay, Dong, Yuhui, Potter, Clinton S, Carragher, Bridget, Caffrey, Martin, Jiang, Hualiang, Chapman, Henry N., Spence, John C. H., Fromme, Petra, Weierstall, Uwe, Ernst, Oliver P., Katritch, Vsevolod, Gurevich, Vsevolod V., Griffin, Patrick R., Hubbell, Wayne L., Stevens, Raymond C., Cherezov, Vadim, Melcher, Karsten, Xu, H. Eric
Wydane w Nature (2015)